Publications

Patel AY, Zarrineh P, Sheth JH, Mohan S, Iqbal M, Nagarajan S, Subtype-specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers, bioRxiv 2025.02.18.638890; https://doi.org/10.1101/2025.02.18.638890

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Hasselluhn MC, Schlösser D, Versemann L, Schmidt GE, Ulisse M, Oschwald J, et al. An NFATc1/SMAD3/cJUN complex restricted to SMAD4-deficient pancreatic cancer guides rational therapies. Gastroenterology [Internet]. 2023 Oct 30 [cited 2023 Nov 1];0(0). Available from: https://www.gastrojournal.org/article/S0016-5085(23)05202-2/fulltext

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​Siersbæk R, Scabia V, Nagarajan S, Chernukhin I, Papachristou EK, Broome R, et al. IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis. Cancer Cell. 2020 Sep 14;38(3):412-423.e9.

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Nagarajan S, Rao SV*, Sutton J*, Cheeseman D*, Dunn S, Papachristou EK, Prada J-EG, Couturier D-L, Kumar S, Kishore K, Chilamakuri CSR, Glont S-E, Archer Goode E, Brodie C, Guppy N, Natrajan R, Bruna A, Caldas C, Russell A, Siersbæk R, Yusa K, Chernukhin I, Carroll JS, ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response,        Nature Genetics, 2020, 52, 187–197

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Nagarajan S, Bedi U, Budida A, Hamdan FH, Mishra VK, Najafova Z, et al. BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells. Nucleic Acids Res. 2017 Apr 7;45(6):3130–45.

Jozwik KM, Chernukhin I, Serandour AA, Nagarajan S#, Carroll JS#, FOXA1 directs H3K4 monomethylation at enhancers via recruitment of the methyltransferase MLL3  Cell Reports, 2016, 17 (10), 2715–2723, # Co-corresponding author 

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Nagarajan S, Benito E, Fischer A, Johnsen SA. H4K12ac is regulated by estrogen receptor-alpha and is associated with BRD4 function and inducible transcription. Oncotarget. 2015 Mar 30;6(9):7305–17.

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Nagarajan S, Hossan T, Alawi M, Najafova Z, Indenbirken D, Bedi U, et al. Bromodomain Protein BRD4 Is Required for Estrogen Receptor-Dependent Enhancer Activation and Gene Transcription. Cell Reports. 2014 Jul 24;8(2):460–9. 

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